Saturday, June 19, 2010

Thalassemia Major and Thalassemia Minor

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Thalassemia
Thalassemia is a disease caused by genetic abnormalities, and is derived from her parents. Thalassemia is divided into two types, namely thalassemia major and thalassemia minor.

Symptoms of thalassemia major:

1. Pale
2. Enlarged abdomen, caused by enlargement of the liver and spleen.
3. Iron accumulation in several organs (skin, heart, lung, endocrine glands, including pancreas gland growth and insulin-forming). They resulted in failure to thrive, stunted growth of secondary sex (thereby making them sterile), a dusky skin, bones brittle, and easily broken.

While in the minor talassemia occur without symptoms. However, when peripheral blood examination, the patient will get the results showed a low Hb level and red blood cell size is small. Thalassemia minor often suspected as anemia, which occurs due to lack of nutrients (iron deficiency anemia).

As mentioned above, thalassemia major and thalassemia minor due to genetic abnormalities. However thalassemia major is derived from both parents who each have a thalassemia gene.

Handling needs to be done for patients with thalassemia major are:
1. Perform blood transfusion for life.
2. Removing the iron that accumulates due to regular blood transfusions regularly.
3. Monitor heart function, lung, bone, pancreas, and other endocrine glands.
4. Bone marrow transplantation for patients with thalassemia major makes a thalassemia minor.
5. Psychosocial handling for thalassemia patients and their families.

While handling needs to be done in patients with thalassemia minor are:
1. Perform a lifetime of blood transfusions in certain circumstances.
2. Removing the iron that accumulates due to regular blood transfusions regularly.
3. Psychosocial handling for patients and their families.

Not found in medicines that can cope with thalassemia minor. However, proven effective therapy to cure disease.
source : info-sehat.com

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